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Pathology
may offer unique opportunities to evaluate the role of sensory feedback
in human motor control processes, especially patients suffering partial
or acute loss of proprioception and touch, as observed in the sensory
neuropathy syndrome. This syndrome, which follows an acute infection of
unknown origin, is presumably associated with a cross-reaction between
antibody to the foreign antigen and the sensory neurons of larger myelinated
fibers. The structural loss is definitive and most patients do not show
any recovery of nerve function, although they generally develop compensatory
strategies by using substitutive feedback channels, mainly visual. Studies
of such cases may lead to a better understanding of the way and the extent
to which cognitive strategies and supplementary sources of information
overcome the lack of muscular and cutaneous proprioception in the control
of coordinated actions. This site aims at promoting access to the main
results obtained on the canadian patient GL (Pr Yves Lamarre, Hôtel-Dieu,
Montréal) in a wide range of clinical and experimental investigations
already made by different groups all over the world.
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